#summary Lateral Mammillary Nucleus @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaFMM] -> [BrainRegionFMM_FD_MB_LMB] ---- This page covers biological details of component Lateral Mammillary Nucleus. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Forebrain Diencephalon -> [BrainCenterFD_HT Hypothalamus] (FD.HT) -> Mammillary Body (FD.MB) -> [BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus] (FMM.FD.MB.LMB) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaFMM Forebrain - Memory Management Area] (FMM) * *Area circuit*: Orienting Control (MMAORIENT) * *Role*: processor.memory.space * *Function*: Generate theta rythm and relay to HC * *Notes to function*: * Memory, recognition, spatial awareness, and interpreting the context of events (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/FMM.FD.MB.LMB.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FT_SEP_MED FAM.FT.SEP.MED] || Medial Septal Nucleus || modulatory-ach || uncertain ||[http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)] || || [BrainAreaFMM FMM] || [BrainRegionFMM_NC_PH_PAS FMM.NC.PH.PAS] || Parasubiculum || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Mammillary bodies: two memory systems in one (PAS -> LMB)] || || || [BrainRegionFMM_NC_PH_POS FMM.NC.PH.POS] || Postsubiculum || excitatory-glu || uncertain ||[http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (PSUB -> LMB)] || || || [BrainRegionFMM_NC_PH_PRS FMM.NC.PH.PRS] || Presubiculum || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Mammillary bodies: two memory systems in one (PRS -> LMB)] || || [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_SUM LAC.FD.HT.SUM] || Supramammillary Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Mammillary bodies: two memory systems in one (SupraMM -> LMB)] || || [BrainAreaLMC LMC] || [BrainRegionLMC_HT_TG_LDT LMC.HT.TG.LDT] || Laterodorsal Tegmental Nucleus || modulatory-ach || uncertain ||[http://ahuman.org/svn/ahengine/research/articles/2009-Hippocampus-Thesis.pdf Hippocampal Formation (DTN -> LMam)] || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaFMM FMM] || [BrainRegionFMM_FD_TH_AD FMM.FD.TH.AD] || Anterodorsal Nucleus || excitatory-glu || uncertain || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (LMB -> AD)] || || [BrainAreaLLC LLC] || [BrainRegionLLC_HT_PRF_RTMG LLC.HT.PRF.RTMG] || Pontine Reticulotegmental Nucleus || excitatory-glu || uncertain || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/mb.jpg Mammillary Body (LMB -> RTG)] || || [BrainAreaLMC LMC] || [BrainRegionLMC_HT_TG_LDT LMC.HT.TG.LDT] || Laterodorsal Tegmental Nucleus || excitatory-glu || uncertain || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (LMB -> DTN)] || = Thirdparty Circuits = (generated) * [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference] (CT.HEAD-DIRECTION) AD=[BrainRegionFMM_FD_TH_AD Anterodorsal Nucleus,FMM.FD.TH.AD] DTN=[BrainRegionLMC_HT_TG_LDT Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG] EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) IPD=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD] LD=[BrainRegionFMM_FD_TH_LD Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD] LHAB=[BrainCenterFAM_FD_HB Habenula,FAM.FD.HB] LMB=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] MVSN=[BrainRegionLPC_HT_MVBN Medial Vestibular Nucleus,LPC.HT.MVBN] NPRP=[BrainRegionLRC_HL_NPH Prepositus Nucleus,LRC.HL.NPH] PC=Parietal Lobe,NC.LOBE.PAR PRHC=[BrainRegionFMM_NC_PH_POR Postrhinal Cortex,FMM.NC.PH.POR] PSUB=[BrainRegionFMM_NC_PH_POS Postsubiculum,FMM.NC.PH.POS] RSP=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC] SUPGEN=[BrainRegionNSA_FD_TH_SG Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG] VC=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC] unavailable * [http://learnmem.cshlp.org/content/14/11/714/F1.large.jpg Attractor Network in Hippocampus] - see [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Reference] (CT.ATTRACTOR-NETWORK) AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) DG=[BrainRegionFMM_FT_HC_DG Dentate Gyrus,FMM.FT.HC.DG] EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) MBIN=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] MBOUT=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] NACC=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia]) PERI=[BrainRegionFMM_NC_PH_PER Perirhinal Cortex,FMM.NC.PH.PER] PRESUB=[BrainRegionFMM_NC_PH_PRS Presubiculum,FMM.NC.PH.PRS] SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] SUB=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) unavailable * [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f2.jpg Mammillary bodies: two memory systems in one] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Reference] (CT.MB-MEMORY) ADTH=[BrainRegionFMM_FD_TH_AD Anterodorsal Nucleus,FMM.FD.TH.AD] AMTH=[BrainRegionNCP_FD_TH_AM Anteromedial Nucleus,NCP.FD.TH.AM] AVTH=[BrainRegionFMM_FD_TH_AV Anteroventral Nucleus,FMM.FD.TH.AV] DTN=[BrainRegionLMC_HT_TG_LDT Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT] LMB=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) PAS=[BrainRegionFMM_NC_PH_PAS Parasubiculum,FMM.NC.PH.PAS] POS=[BrainRegionFMM_NC_PH_POS Postsubiculum,FMM.NC.PH.POS] PRS=[BrainRegionFMM_NC_PH_PRS Presubiculum,FMM.NC.PH.PRS] SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] SUB=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) SupraMM=[BrainRegionLAC_FD_HT_SUM Supramammillary Nucleus,LAC.FD.HT.SUM] TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (see [BrainCenterFD_HT Hypothalamus]) VTN=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/mb.jpg Mammillary Body] (unknown reference) (CT.LMB-MMB) LMB=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] RTG=[BrainRegionLLC_HT_PRF_RTMG Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/brain/HF.jpg Hippocampal Formation] - see [article:2009-Hippocampus-Thesis.pdf Reference] (CT.HIPPOCAMPAL-FORMATION) ATN=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) DG=[BrainRegionFMM_FT_HC_DG Dentate Gyrus,FMM.FT.HC.DG] DTN=[BrainRegionLMC_HT_TG_LDT Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT] EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) LDN=[BrainRegionFMM_FD_TH_LD Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD] LMam=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] PoS=[BrainRegionFMM_NC_PH_POS Postsubiculum,FMM.NC.PH.POS] Rsp=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC] Sub=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) unavailable = References = (generated) * http://www.scholarpedia.org/article/Head_direction_cells * http://learnmem.cshlp.org/content/14/11/714/F1.expansion * http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html * article:2009-Hippocampus-Thesis.pdf