#summary Substantia Nigra Pars Compacta Medial
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaFEC] -> [BrainRegionFEC_FT_SNC_MED]
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This page covers biological details of component Substantia Nigra Pars Compacta Medial.
Region is part of aHuman target integrated biological model.

  * *Top-down path to region*: Forebrain Telencephalon -> [BrainCenterFEC_FT_BG Basal Ganglia] (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Compacta (FEC.FT.SNC) -> [BrainRegionFEC_FT_SNC_MED Substantia Nigra Pars Compacta Medial] (FEC.FT.SNC.MED) (see [OverallMindMaps Mind Maps])
  * *Type*: nucleus
  * *Quality*: L0
  * *Brain area*: [BrainAreaFEC Forebrain - Execution Control Area] (FEC)
  * *Area circuit*: Motor Motivational Salience (FECLM)
  * *Role*: basal.ganglia.nigracompacta
  * *Function*: motivational loop
  * *Notes to function*: 
   * VP, ventral circuits
(generated)
= Components =
(generated)


  * no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/FEC.FT.SNC.MED.dot.png

*Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FT_BNST FAM.FT.BNST] || Bed Nucleus of Stria Terminalis || excitatory-glu || uncertain ||(unknown reference) ||
|| [BrainAreaFEC FEC] || [BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE] || Nucleus Accumbens Core || inhibitory-gaba || uncertain ||(unknown reference) ||
||  || [BrainRegionFEC_FT_GPI_RM FEC.FT.GPI.RM] || Globus Pallidus Internal Rostromedial || inhibitory-gaba || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] ||
||  || [BrainRegionFEC_FT_SNR_MED FEC.FT.SNR.MED] || Substantia Nigra Pars Reticulata Medial || inhibitory-gaba || uncertain ||(unknown reference) ||
||  || [BrainRegionFEC_HT_TG_RMTG FEC.HT.TG.RMTG] || Rostromedial Tegmental Nucleus || inhibitory-gaba || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> SNc, abstract)] ||
|| [BrainAreaLMC LMC] || [BrainRegionLMC_HT_LC LMC.HT.LC] || Locus Coeruleus || modulatory-ne || uncertain ||(unknown reference) ||

*Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM] || Medial Central Amygdaloid Nucleus || modulatory-da || uncertain || (unknown reference) ||
|| [BrainAreaFEC FEC] || [BrainRegionFEC_FT_ACC_SH FEC.FT.ACC.SH] || Nucleus Accumbens Shell || modulatory-da || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] ||
|| [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_SUM LAC.FD.HT.SUM] || Supramammillary Nucleus || modulatory-da || uncertain || (unknown reference) ||
|| [BrainAreaLRC LRC] || [BrainRegionLRC_HT_PRF_PVR LRC.HT.PRF.PVR] || Parvocellular Reticular Nucleus || modulatory-da || uncertain || (unknown reference) ||

= Thirdparty Circuits =
(generated)

  * [http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey] - see [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Reference] (CM.SN-PPN)

 GPe=Globus Pallidus External,FEC.FT.GPE (see [BrainCenterFEC_FT_BG Basal Ganglia])
 GPi=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia])
 PPN=[BrainRegionLMC_HT_TG_PPN Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN]
 SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia])
 SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [BrainCenterFEC_FT_BG Basal Ganglia])
 STN=Subthalamic Nucleus,FEC.FD.STN (see [BrainCenterFEC_FD_STA Subthalamus Area])
<img src="http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png" alt="unavailable" style="max-width: 100%;">

  * [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN)

 CPu=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia])
 EP=[BrainRegionFAM_FT_EPF Endopiriform Nucleus,FAM.FT.EPF]
 Hippo=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 IPN=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD]
 L=Lateral Habenula,FAM.FD.LHB (see [BrainCenterFAM_FD_HB Habenula])
 LH=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
 M=[BrainRegionFAM_FD_MHB Medial Habenula,FAM.FD.MHB]
 NAc=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia])
 PAG=[BrainRegionLMC_MM_PAG Periaqueductal Gray Matter,LMC.MM.PAG]
 Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [BrainCenterHL_RF Medullary Reticular Formation])
 SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia])
 Septum=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP]
 VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
<img src="http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg" alt="unavailable" style="max-width: 100%;">


= References =
(generated)

  * http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs
  * http://jn.physiology.org/content/107/10/2633