#summary Nucleus Accumbens Shell
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaFEC] -> [BrainRegionFEC_FT_ACC_SH]
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This page covers biological details of component Nucleus Accumbens Shell.
Region is part of aHuman target integrated biological model.
* *Top-down path to region*: Forebrain Telencephalon -> [BrainCenterFEC_FT_BG Basal Ganglia] (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> [BrainRegionFEC_FT_ACC_SH Nucleus Accumbens Shell] (FEC.FT.ACC.SH) (see [OverallMindMaps Mind Maps])
* *Type*: nucleus
* *Quality*: L0
* *Brain area*: [BrainAreaFEC Forebrain - Execution Control Area] (FEC)
* *Area circuit*: Cognitive Motivational Salience (FECAF)
* *Role*: basal.ganglia.striatum
* *Function*: cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects
(generated)
= Components =
(generated)
* no child items defined
= Connectivity =
(generated)
http://ahuman.org/svn/ahwiki/images/dot/FEC.FT.ACC.SH.dot.png
*Inbound Region Connections:*
|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFEC FEC] || [BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT] || Substantia Nigra Pars Compacta Lateral || modulatory-da || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] ||
|| || [BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED] || Substantia Nigra Pars Compacta Medial || modulatory-da || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] ||
|| [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_VM LAC.FD.HT.VM] || Ventromedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract)] ||
|| [BrainAreaLMC LMC] || [BrainRegionLMC_MM_VTA LMC.MM.VTA] || Ventral Tegmental Area || modulatory-da || uncertain ||[http://www.impulsecontroldisorders.org/html/cravings.html Craving (VTA -> NACC, abstract)] ||
|| [BrainAreaLPC LPC] || [BrainRegionLPC_HL_SOL LPC.HL.SOL] || Solitary Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (NTS -> NAc, abstract)] ||
|| || [BrainRegionLPC_HT_PRF_PB LPC.HT.PRF.PB] || Parabrachial Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)] ||
|| [BrainAreaNCP NCP] || [BrainRegionNCP_NC_MPL_PSCG NCP.NC.MPL.PSCG] || Posterior Cingulate Cortex || excitatory-glu || uncertain ||(unknown reference) ||
|| [BrainAreaNDM NDM] || [BrainRegionNDM_NC_AL_VACG NDM.NC.AL.VACG] || Ventral Anterior Cingulate Area || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)] ||
*Outbound Region Connections:*
|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FD_MHB FAM.FD.MHB] || Medial Habenula || inhibitory-gaba || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> M, abstract)] ||
|| [BrainAreaFEC FEC] || [BrainRegionFEC_FT_IPAC_LT FEC.FT.IPAC.LT] || Lateral Interstitial Anterior Commissural Nucleus || inhibitory-gaba || uncertain || (unknown reference) ||
|| || [BrainRegionFEC_FT_VP_VM FEC.FT.VP.VM] || Ventral Pallidum Ventromedial || inhibitory-gaba || uncertain || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> VPAL, abstract)] ||
|| [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_LTN LAC.FD.HT.LTN] || Lateral Hypothalamic Nucleus || inhibitory-gaba || uncertain || (unknown reference) ||
|| [BrainAreaLMC LMC] || [BrainRegionLMC_FT_NBM LMC.FT.NBM] || Basal Nucleus of Meynert || inhibitory-gaba || uncertain || [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (NACC -> nBM, abstract)] ||
= Thirdparty Circuits =
(generated)
* [http://neurowiki2012.wikispaces.com/file/view/Reward_circuit.jpg/315908202/Reward_circuit.jpg Reward circuit of human brain] - see [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reference] (CF.REWARD-CIRCUIT)
AM=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM]
HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation])
NACC=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia])
PFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex])
VPAL=Ventral Pallidum,FEC.FT.VP (see [BrainCenterFEC_FT_BG Basal Ganglia])
VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
* [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia])
EP=[BrainRegionFAM_FT_EPF Endopiriform Nucleus,FAM.FT.EPF]
Hippo=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation])
IPN=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD]
L=Lateral Habenula,FAM.FD.LHB (see [BrainCenterFAM_FD_HB Habenula])
LH=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
M=[BrainRegionFAM_FD_MHB Medial Habenula,FAM.FD.MHB]
NAc=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia])
PAG=[BrainRegionLMC_MM_PAG Periaqueductal Gray Matter,LMC.MM.PAG]
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [BrainCenterHL_RF Medullary Reticular Formation])
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia])
Septum=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP]
VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
* [http://www.impulsecontroldisorders.org/images/8-Urges9proof.jpg Craving] - see [http://www.impulsecontroldisorders.org/html/cravings.html Reference] (CF.CRAVING)
NACC=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia])
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex])
SNr=[BrainRegionFEC_FT_SNR_MED Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED]
VPAL=Ventral Pallidum,FEC.FT.VP (see [BrainCenterFEC_FT_BG Basal Ganglia])
VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
* [http://www.expertsmind.com/CMSImages/250_Affective%20basal%20ganglia%20circuit.png Affective basal ganglia circuit] - see [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Reference] (CF.AFFECTIVE-BG)
NACC=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia])
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex])
nBM=[BrainRegionLMC_FT_NBM Basal Nucleus of Meynert,LMC.FT.NBM]
= References =
(generated)
* http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity
* http://jn.physiology.org/content/107/10/2633
* http://www.impulsecontroldisorders.org/html/cravings.html
* http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx