#summary Subthalamic Nucleus Medial @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaFEC] -> [BrainRegionFEC_FD_STN_MED] ---- This page covers biological details of component Subthalamic Nucleus Medial. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Forebrain Diencephalon -> [BrainCenterFEC_FD_STA Subthalamus Area] (FEC.FD.STA) -> Subthalamic Nucleus (FEC.FD.STN) -> [BrainRegionFEC_FD_STN_MED Subthalamic Nucleus Medial] (FEC.FD.STN.MED) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaFEC Forebrain - Execution Control Area] (FEC) * *Area circuit*: Motor Extensor Loop (FECME) * *Role*: basal.ganglia.subthalamus * *Function*: Motor Extensor loop (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/FEC.FD.STN.MED.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaLMC LMC] || [BrainRegionLMC_HT_TG_PPN LMC.HT.TG.PPN] || Pedunculopontine Tegmental Nuclei || modulatory-ach || uncertain ||[http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> STN, abstract)] || || [BrainAreaNMA NMA] || [BrainRegionNMA_NC_SMC_F6 NMA.NC.SMC.F6] || Pre-Supplementary Motor Area || excitatory-glu || uncertain ||[http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml Serotonin regulation of subthalamic neurons (CTX -> STN, abstract)] || || [BrainAreaNPE NPE] || [BrainRegionNPE_NC_PMC_AFEF NPE.NC.PMC.AFEF] || Anterior Frontal Eye Field || excitatory-glu || uncertain ||[http://www.neurology.org/content/70/21/1991/F2.expansion.html Functional subdivisions of the subthalamic nucleus (FEF -> STN, abstract)] || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaFEC FEC] || [BrainRegionFEC_FT_GPE_MED FEC.FT.GPE.MED] || Globus Pallidus External Medial || excitatory-glu || uncertain || [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (STN -> GPe, abstract)] || || || [BrainRegionFEC_FT_GPI_MED FEC.FT.GPI.MED] || Globus Pallidus Internal Medial || excitatory-glu || uncertain || [http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html Basal Ganglia Activity (STN -> GPi, abstract)] || || || [BrainRegionFEC_FT_SNR_DL FEC.FT.SNR.DL] || Substantia Nigra Pars Reticulata Dorsolateral || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Saccadic Vision (STN -> SNpr, abstract)] || = Thirdparty Circuits = (generated) * [http://www.nature.com/nrn/journal/v5/n3/images/nrn1345-i1.jpg Saccadic Vision] - see [http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Reference] (CP.SACCADIC-VISION) BG=[BrainCenterFEC_FT_BG Basal Ganglia,FEC.FT.BG] CN=Caudate Nucleus,FEC.FT.CN (see [BrainCenterFEC_FT_BG Basal Ganglia]) CR=Cerebellum,LLC.HT.CR (see [BrainCenterLLC_HT_CRC Cerebellar Complex]) FrontalCortex=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see [BrainCenterFEC_FT_BG Basal Ganglia]) LGN=[BrainRegionNSA_FD_LGN Lateral Geniculate Nucleus,NSA.FD.LGN] LIP=[BrainRegionNPE_NC_IPS_LIP Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP] RF=[BrainCenterHT_RF Pontine Reticular Formation,HT.RF] Retina=[BrainRegionLPC_FD_RT Retinal Nucleus,LPC.FD.RT] SCi=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) SCs=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) SNpr=[BrainRegionFEC_FT_SNR_DL Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL] STN=Subthalamic Nucleus,FEC.FD.STN (see [BrainCenterFEC_FD_STA Subthalamus Area]) Thalamus=Thalamus,FD.TH VisualCortex=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC] unavailable * [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/graphic/revneuro-2014-0004_fig1.jpg Serotonin regulation of subthalamic neurons] - see [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml Reference] (CM.SUBTHALAMUS) CTX=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see [BrainCenterFEC_FT_BG Basal Ganglia]) GPi=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia]) PPN=[BrainRegionLMC_HT_TG_PPN Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN] SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [BrainCenterFEC_FT_BG Basal Ganglia]) STN=Subthalamic Nucleus,FEC.FD.STN (see [BrainCenterFEC_FD_STA Subthalamus Area]) unavailable * [http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey] - see [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Reference] (CM.SN-PPN) GPe=Globus Pallidus External,FEC.FT.GPE (see [BrainCenterFEC_FT_BG Basal Ganglia]) GPi=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia]) PPN=[BrainRegionLMC_HT_TG_PPN Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN] SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia]) SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [BrainCenterFEC_FT_BG Basal Ganglia]) STN=Subthalamic Nucleus,FEC.FD.STN (see [BrainCenterFEC_FD_STA Subthalamus Area]) unavailable * [http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou_2b.jpg Basal Ganglia Activity] - see [http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html Reference] (CM.BASAL-GANGLIA-ACTIVITY) GPi=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia]) GPo=Globus Pallidus External,FEC.FT.GPE (see [BrainCenterFEC_FT_BG Basal Ganglia]) M1=[BrainRegionNMA_NC_MC Motor Cortex,NMA.NC.MC] PMC=[BrainCenterNC_PMC Premotor Cortex,NC.PMC] PU=Dorsal Putamen,FEC.FT.DPU (see [BrainCenterFEC_FT_BG Basal Ganglia]) S1=[BrainRegionNCP_NC_PG_S1 Primary Somatosensory Cortex,NCP.NC.PG.S1] SMC=[BrainCenterNMA_NC_SMC Supplementary Motor Cortex,NMA.NC.SMC] SN=Substantia Nigra,FEC.FT.SN (see [BrainCenterFEC_FT_BG Basal Ganglia]) STN=Subthalamic Nucleus,FEC.FD.STN (see [BrainCenterFEC_FD_STA Subthalamus Area]) VLo=[BrainRegionNMA_FD_TH_VL Ventral Lateral Nucleus,NMA.FD.TH.VL] unavailable = References = (generated) * http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html * http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml * http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs * http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html