#summary Lateral Septal Nucleus @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaFAM] -> [BrainRegionFAM_FT_SEP_LT] ---- This page covers biological details of component Lateral Septal Nucleus. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> [BrainCenterFAM_FT_SEP Septal Nuclei] (FAM.FT.SEP) -> Dorsal Septal Nucleus (FAM.FT.SEP.DS) -> Lateral Septal Group (FAM.FT.SEP.LG) -> [BrainRegionFAM_FT_SEP_LT Lateral Septal Nucleus] (FAM.FT.SEP.LT) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaFAM Forebrain - Affective Motivations Area] (FAM) * *Area circuit*: Solving Fight-Flight Dilemma (FAMXFFD) * *Role*: processor.affective * *Function*: promote active stress coping behavior (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/FAM.FT.SEP.LT.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM] || Medial Central Amygdaloid Nucleus || excitatory-glu || uncertain ||(unknown reference) || || || [BrainRegionFAM_FT_AM_MPV FAM.FT.AM.MPV] || Medial Posterior Ventral Amygdaloid Nucleus || inhibitory-gaba || uncertain ||(unknown reference) || || [BrainAreaFMM FMM] || [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D] || Distal CA1 of Hippocampus || excitatory-glu || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Hippo -> Septum, abstract)] || || [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_PN LAC.FD.HT.PN] || Posterior Hypothalamic Nucleus || excitatory-glu || uncertain ||(unknown reference) || || || [BrainRegionLAC_FD_HT_TBM LAC.FD.HT.TBM] || Tuberomammillary Nucleus || excitatory-glu || uncertain ||(unknown reference) || || [BrainAreaLMC LMC] || [BrainRegionLMC_MM_RP_SUC LMC.MM.RP.SUC] || Superior Central Raphe Nucleus || modulatory-5ht || uncertain ||(unknown reference) || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED] || Lateral Habenula Medial Part || inhibitory-gaba || uncertain || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LS -> LHbM)] || || [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_VLPO LAC.FD.HT.VLPO] || Ventrolateral Preoptic Nucleus || inhibitory-gaba || uncertain || [http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)] || || [BrainAreaNDM NDM] || [BrainRegionNDM_FD_TH_PV NDM.FD.TH.PV] || Paraventricular Nucleus of Thalamus || inhibitory-gaba || uncertain || (unknown reference) || = Thirdparty Circuits = (generated) * [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f4.jpg Medial mammillary nucleus and theta rhythm] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Reference] (CT.MMB-THETA) AVTH=[BrainRegionFMM_FD_TH_AV Anteroventral Nucleus,FMM.FD.TH.AV] HF=[BrainCenterFMM_FT_HF Hippocampal Formation,FMM.FT.HF] MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] RSP=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC] SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] SupraMM=[BrainRegionLAC_FD_HT_SUM Supramammillary Nucleus,LAC.FD.HT.SUM] VTN=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] unavailable * [http://www.thebrainlabs.com/Images/cingulate_gyrus.gif Cingulate Gyrus] - see [http://www.thebrainlabs.com Reference] (CT.CINGULATE-CORTEX) CG=[BrainRegionNCP_NC_MPL_PSCG Posterior Cingulate Cortex,NCP.NC.MPL.PSCG] ET=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) HT=[BrainCenterFD_HT Hypothalamus,FD.HT] MB=Mammillary Body,FD.MB (see [BrainCenterFD_HT Hypothalamus]) SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] TH=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) unavailable * [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference] (CF.HB-DA5HT) DBB=[BrainRegionFAM_FT_SEP_DBB Diagonal Band of Broca,FAM.FT.SEP.DBB] DRN=[BrainRegionLMC_MM_RP_DRN Dorsal Raphe Nucleus,LMC.MM.RP.DRN] GPb=Dorsal Pallidum,FEC.FT.DP (see [BrainCenterFEC_FT_BG Basal Ganglia]) IPN=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD] LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] LHbL=[BrainRegionFAM_FD_LHB_LT Lateral Habenula Lateral Part,FAM.FD.LHB.LT] LHbM=[BrainRegionFAM_FD_LHB_MED Lateral Habenula Medial Part,FAM.FD.LHB.MED] LPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO] LS=[BrainRegionFAM_FT_SEP_LT Lateral Septal Nucleus,FAM.FT.SEP.LT] MHb=[BrainRegionFAM_FD_MHB Medial Habenula,FAM.FD.MHB] MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see [BrainCenterHL_RF Medullary Reticular Formation]) MS=[BrainRegionFAM_FT_SEP_MED Medial Septal Nucleus,FAM.FT.SEP.MED] PS=Posterior Septal Group,FAM.FT.SEP.PG (see [BrainCenterFAM_FT_SEP Septal Nuclei]) RMTg=[BrainRegionFEC_HT_TG_RMTG Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG] SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia]) VP=Ventral Pallidum,FEC.FT.VP (see [BrainCenterFEC_FT_BG Basal Ganglia]) VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] unavailable = References = (generated) * http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html * http://www.thebrainlabs.com * http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html