#summary Diagonal Band of Broca
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaFAM] -> [BrainRegionFAM_FT_SEP_DBB]
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This page covers biological details of component Diagonal Band of Broca.
Region is part of aHuman target integrated biological model.

  * *Top-down path to region*: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> [BrainCenterFAM_FT_SEP Septal Nuclei] (FAM.FT.SEP) -> Dorsal Septal Nucleus (FAM.FT.SEP.DS) -> Medial Septal Group (FAM.FT.SEP.MG) -> [BrainRegionFAM_FT_SEP_DBB Diagonal Band of Broca] (FAM.FT.SEP.DBB) (see [OverallMindMaps Mind Maps])
  * *Type*: nucleus
  * *Quality*: L0
  * *Brain area*: [BrainAreaFAM Forebrain - Affective Motivations Area] (FAM)
  * *Area circuit*: Memory Formation Affective Focus (FAMXMF)
  * *Role*: processor.affective.memory
  * *Function*: involved in generation of theta waves in hippocampus
  * *Notes to function*: 
   * ACh and GABA
   *  ventral group - from stria terminalis to/from MFB
(generated)
= Components =
(generated)


  * no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/FAM.FT.SEP.DBB.dot.png

*Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_SUM LAC.FD.HT.SUM] || Supramammillary Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)] ||
|| [BrainAreaLMC LMC] || [BrainRegionLMC_HT_LC LMC.HT.LC] || Locus Coeruleus || modulatory-ne || uncertain ||(unknown reference) ||

*Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED] || Lateral Habenula Medial Part || inhibitory-gaba || uncertain || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (DBB -> LHbM)] ||
||  || [BrainRegionFAM_FD_MHB FAM.FD.MHB] || Medial Habenula || inhibitory-gaba || uncertain || [http://www.scholarpedia.org/article/Habenula Habenula Connections (DBB -> MHb)] ||
|| [BrainAreaFMM FMM] || [BrainRegionFMM_FD_MB_MMB FMM.FD.MB.MMB] || Medial Mammillary Nucleus || inhibitory-gaba || uncertain || [http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)] ||
||  || [BrainRegionFMM_FT_HC_CA2 FMM.FT.HC.CA2] || Dorsolateral Cornu Ammonis of Hippocampus || inhibitory-gaba || uncertain || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)] ||
|| [BrainAreaNDM NDM] || [BrainRegionNDM_NC_AL_VMPFC NDM.NC.AL.VMPFC] || Ventromedial Prefrontal Cortex || inhibitory-gaba || uncertain || (unknown reference) ||

= Thirdparty Circuits =
(generated)

  * [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f4.jpg Medial mammillary nucleus and theta rhythm] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Reference] (CT.MMB-THETA)

 AVTH=[BrainRegionFMM_FD_TH_AV Anteroventral Nucleus,FMM.FD.TH.AV]
 HF=[BrainCenterFMM_FT_HF Hippocampal Formation,FMM.FT.HF]
 MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB]
 RSP=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC]
 SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP]
 SupraMM=[BrainRegionLAC_FD_HT_SUM Supramammillary Nucleus,LAC.FD.HT.SUM]
 VTN=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
<img src="http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f4.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://www.thebrainlabs.com/Images/cingulate_gyrus.gif Cingulate Gyrus] - see [http://www.thebrainlabs.com Reference] (CT.CINGULATE-CORTEX)

 CG=[BrainRegionNCP_NC_MPL_PSCG Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]
 ET=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex])
 HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 HT=[BrainCenterFD_HT Hypothalamus,FD.HT]
 MB=Mammillary Body,FD.MB (see [BrainCenterFD_HT Hypothalamus])
 SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP]
 TH=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus])
<img src="http://www.thebrainlabs.com/Images/cingulate_gyrus.gif" alt="unavailable" style="max-width: 100%;">

  * [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference] (CF.HB-CONNECTIONS)

 CPu=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia])
 DBB=[BrainRegionFAM_FT_SEP_DBB Diagonal Band of Broca,FAM.FT.SEP.DBB]
 DR=[BrainRegionLMC_MM_RP_DRN Dorsal Raphe Nucleus,LMC.MM.RP.DRN]
 GPi=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia])
 IP=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD]
 LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see [BrainCenterFD_HT Hypothalamus])
 LHb=Lateral Habenula,FAM.FD.LHB (see [BrainCenterFAM_FD_HB Habenula])
 LPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]
 MHb=[BrainRegionFAM_FD_MHB Medial Habenula,FAM.FD.MHB]
 MR=[BrainRegionLMC_MM_RP_SUC Superior Central Raphe Nucleus,LMC.MM.RP.SUC]
 PB=[BrainRegionTARGET_TEA_ENDOCRINE Endocrine Glands,TARGET.TEA.ENDOCRINE]
 S=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP]
 SNc=[BrainRegionFEC_FT_SNC_LT Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]
 VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
<img src="http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg Regulation of the rapid eye movement (REM) sleep by habenular projection] - see [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Reference] (CF.REM-HB)

 DBB=[BrainRegionFAM_FT_SEP_DBB Diagonal Band of Broca,FAM.FT.SEP.DBB]
 DTG=[BrainRegionLMC_HT_TG_LDT Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]
 EPN=[BrainRegionFAM_FT_EPF Endopiriform Nucleus,FAM.FT.EPF]
 GPi=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia])
 LHT=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
 LHbL=[BrainRegionFAM_FD_LHB_LT Lateral Habenula Lateral Part,FAM.FD.LHB.LT]
 LHbM=[BrainRegionFAM_FD_LHB_MED Lateral Habenula Medial Part,FAM.FD.LHB.MED]
 NI=[BrainRegionFAM_HT_TG_NI Incertus Nucleus,FAM.HT.TG.NI]
 RMTg=[BrainRegionFEC_HT_TG_RMTG Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]
 Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [BrainCenterHL_RF Medullary Reticular Formation])
 SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia])
 VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
 VTG=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTG]
<img src="http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference] (CF.HB-DA5HT)

 DBB=[BrainRegionFAM_FT_SEP_DBB Diagonal Band of Broca,FAM.FT.SEP.DBB]
 DRN=[BrainRegionLMC_MM_RP_DRN Dorsal Raphe Nucleus,LMC.MM.RP.DRN]
 GPb=Dorsal Pallidum,FEC.FT.DP (see [BrainCenterFEC_FT_BG Basal Ganglia])
 IPN=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD]
 LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
 LHbL=[BrainRegionFAM_FD_LHB_LT Lateral Habenula Lateral Part,FAM.FD.LHB.LT]
 LHbM=[BrainRegionFAM_FD_LHB_MED Lateral Habenula Medial Part,FAM.FD.LHB.MED]
 LPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]
 LS=[BrainRegionFAM_FT_SEP_LT Lateral Septal Nucleus,FAM.FT.SEP.LT]
 MHb=[BrainRegionFAM_FD_MHB Medial Habenula,FAM.FD.MHB]
 MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see [BrainCenterHL_RF Medullary Reticular Formation])
 MS=[BrainRegionFAM_FT_SEP_MED Medial Septal Nucleus,FAM.FT.SEP.MED]
 PS=Posterior Septal Group,FAM.FT.SEP.PG (see [BrainCenterFAM_FT_SEP Septal Nuclei])
 RMTg=[BrainRegionFEC_HT_TG_RMTG Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]
 SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia])
 VP=Ventral Pallidum,FEC.FT.VP (see [BrainCenterFEC_FT_BG Basal Ganglia])
 VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
<img src="http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg" alt="unavailable" style="max-width: 100%;">


= References =
(generated)

  * http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html
  * http://www.thebrainlabs.com
  * http://www.scholarpedia.org/article/Habenula
  * http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full
  * http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html