#summary Lateral Habenula Lateral Part @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaFAM] -> [BrainRegionFAM_FD_LHB_LT] ---- This page covers biological details of component Lateral Habenula Lateral Part. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Forebrain Diencephalon -> [BrainCenterFAM_FD_HB Habenula] (FAM.FD.HB) -> Lateral Habenula (FAM.FD.LHB) -> [BrainRegionFAM_FD_LHB_LT Lateral Habenula Lateral Part] (FAM.FD.LHB.LT) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaFAM Forebrain - Affective Motivations Area] (FAM) * *Area circuit*: Acquisition of Avoidance Responses (FAMXAA) * *Role*: processor.affective.avoidance * *Function*: Encoding negative feedback, direct, Pallidal (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/FAM.FD.LHB.LT.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FT_EPF FAM.FT.EPF] || Endopiriform Nucleus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (EPN -> LHbL)] || || [BrainAreaFEC FEC] || [BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE] || Nucleus Accumbens Core || inhibitory-gaba || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> L, abstract)] || || || [BrainRegionFEC_FT_GPI_DS FEC.FT.GPI.DS] || Globus Pallidus Internal Dorsal || inhibitory-gaba || uncertain ||[http://www.scholarpedia.org/article/Habenula Habenula Connections (GPi -> LHb, abstract)] || || [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_LTN LAC.FD.HT.LTN] || Lateral Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)] || || || [BrainRegionLAC_FD_HT_VLPO LAC.FD.HT.VLPO] || Ventrolateral Preoptic Nucleus || excitatory-glu || uncertain ||[http://www.scholarpedia.org/article/Habenula Habenula Connections (LPO -> LHb, abstract)] || || [BrainAreaLMC LMC] || [BrainRegionLMC_HT_LC LMC.HT.LC] || Locus Coeruleus || modulatory-ne || uncertain ||[http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)] || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaFEC FEC] || [BrainRegionFEC_HT_TG_RMTG FEC.HT.TG.RMTG] || Rostromedial Tegmental Nucleus || excitatory-glu || uncertain || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbL -> RMTg)] || = Thirdparty Circuits = (generated) * [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference] (CF.HB-DA5HT) DBB=[BrainRegionFAM_FT_SEP_DBB Diagonal Band of Broca,FAM.FT.SEP.DBB] DRN=[BrainRegionLMC_MM_RP_DRN Dorsal Raphe Nucleus,LMC.MM.RP.DRN] GPb=Dorsal Pallidum,FEC.FT.DP (see [BrainCenterFEC_FT_BG Basal Ganglia]) IPN=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD] LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] LHbL=[BrainRegionFAM_FD_LHB_LT Lateral Habenula Lateral Part,FAM.FD.LHB.LT] LHbM=[BrainRegionFAM_FD_LHB_MED Lateral Habenula Medial Part,FAM.FD.LHB.MED] LPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO] LS=[BrainRegionFAM_FT_SEP_LT Lateral Septal Nucleus,FAM.FT.SEP.LT] MHb=[BrainRegionFAM_FD_MHB Medial Habenula,FAM.FD.MHB] MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see [BrainCenterHL_RF Medullary Reticular Formation]) MS=[BrainRegionFAM_FT_SEP_MED Medial Septal Nucleus,FAM.FT.SEP.MED] PS=Posterior Septal Group,FAM.FT.SEP.PG (see [BrainCenterFAM_FT_SEP Septal Nuclei]) RMTg=[BrainRegionFEC_HT_TG_RMTG Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG] SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia]) VP=Ventral Pallidum,FEC.FT.VP (see [BrainCenterFEC_FT_BG Basal Ganglia]) VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] unavailable * [http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg Regulation of the rapid eye movement (REM) sleep by habenular projection] - see [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Reference] (CF.REM-HB) DBB=[BrainRegionFAM_FT_SEP_DBB Diagonal Band of Broca,FAM.FT.SEP.DBB] DTG=[BrainRegionLMC_HT_TG_LDT Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG] EPN=[BrainRegionFAM_FT_EPF Endopiriform Nucleus,FAM.FT.EPF] GPi=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia]) LHT=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] LHbL=[BrainRegionFAM_FD_LHB_LT Lateral Habenula Lateral Part,FAM.FD.LHB.LT] LHbM=[BrainRegionFAM_FD_LHB_MED Lateral Habenula Medial Part,FAM.FD.LHB.MED] NI=[BrainRegionFAM_HT_TG_NI Incertus Nucleus,FAM.HT.TG.NI] RMTg=[BrainRegionFEC_HT_TG_RMTG Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG] Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [BrainCenterHL_RF Medullary Reticular Formation]) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia]) VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] VTG=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTG] unavailable = References = (generated) * http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html * http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full