#summary Premotor Cortex @@[Home] -> [BiologicalLifeResearch] -> [BrainCenterNC_PMC] ---- This page covers biological details of component group Premotor Cortex. Component group is part of aHuman target integrated biological model. * *Top-down path to center*: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Premotor Cortex (NC.PMC) (see [OverallMindMaps Mind Maps]) * *Function*: Selection of appropriate motor plans for voluntary movements (generated) = Components = (generated) *Component items*: * *Frontal Eye Field* (NMA.NC.PMC.FEF): Initiation of eye movements * [BrainRegionNPE_NC_PMC_CFEF Caudal Frontal Eye Field] (NPE.NC.PMC.CFEF): Head and eye movements toward visual stimuli * [BrainRegionNPE_NC_PMC_AFEF Anterior Frontal Eye Field] (NPE.NC.PMC.AFEF): Head and eye movements toward auditory stimuli * *Dorsal Premotor Cortex* (MCA.NC.DPMC) * [BrainRegionNMA_NC_PMC_F2 Dorsal Caudal Premotor Cortex] (NMA.NC.PMC.F2): Guiding reaching * [BrainRegionNMA_NC_PMC_F7 Dorsal Rostral Premotor Cortex] (NMA.NC.PMC.F7): Associate arbitrary sensory stimuli with specific eye movements * *Ventral Premotor Cortex* (MCA.NC.VPMC) * [BrainRegionNMA_NC_PMC_F4 Ventral Caudal Premotor Cortex] (NMA.NC.PMC.F4): Sensory guidance of movement * [BrainRegionNMA_NC_PMC_F5 Ventral Rostral Premotor Cortex] (NMA.NC.PMC.F5): Shaping hand during grasping = Connectivity = (generated) *Internal Regions Connections:* unavailable || *Source Region* || *Target Region* || *Reference* || || [BrainRegionNMA_NC_PMC_F4 Ventral Caudal Premotor Cortex] (NMA.NC.PMC.F4) || [BrainRegionNMA_NC_PMC_F2 Dorsal Caudal Premotor Cortex] (NMA.NC.PMC.F2) || (unknown reference) || || [BrainRegionNMA_NC_PMC_F5 Ventral Rostral Premotor Cortex] (NMA.NC.PMC.F5) || [BrainRegionNMA_NC_PMC_F2 Dorsal Caudal Premotor Cortex] (NMA.NC.PMC.F2) || (unknown reference) || || [BrainRegionNMA_NC_PMC_F7 Dorsal Rostral Premotor Cortex] (NMA.NC.PMC.F7) || [BrainRegionNMA_NC_PMC_F2 Dorsal Caudal Premotor Cortex] (NMA.NC.PMC.F2) || (unknown reference) || || [BrainRegionNPE_NC_PMC_AFEF Anterior Frontal Eye Field] (NPE.NC.PMC.AFEF) || [BrainRegionNMA_NC_PMC_F5 Ventral Rostral Premotor Cortex] (NMA.NC.PMC.F5) || [http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html Cortical Auditory System (PMC8 -> PMC6, abstract)] || || || [BrainRegionNMA_NC_PMC_F7 Dorsal Rostral Premotor Cortex] (NMA.NC.PMC.F7) || (unknown reference) || || [BrainRegionNPE_NC_PMC_CFEF Caudal Frontal Eye Field] (NPE.NC.PMC.CFEF) || [BrainRegionNMA_NC_PMC_F5 Ventral Rostral Premotor Cortex] (NMA.NC.PMC.F5) || (unknown reference) || || || [BrainRegionNPE_NC_PMC_AFEF Anterior Frontal Eye Field] (NPE.NC.PMC.AFEF) || (unknown reference) || *External Connections:* unavailable *External Inbound Center Connections:* || *Source Center* || *Sample Link* || *Reference* || || [BrainCenterFD_TH_CR Cognitive Thalamus] (FD.TH.CR) || [BrainRegionNMA_FD_TH_MDL NMA.FD.TH.MDL] -> [BrainRegionNPE_NC_PMC_AFEF NPE.NC.PMC.AFEF]||[http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Oculomotor decision-making (Thalamus -> FEF, abstract)] || || [BrainCenterFD_TH_MR Motor Thalamus] (FD.TH.MR) || [BrainRegionNMA_FD_TH_VA NMA.FD.TH.VA] -> [BrainRegionNMA_NC_PMC_F2 NMA.NC.PMC.F2]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (TH -> PMC, abstract)] || || [BrainCenterNC_ACG Anterior Cingulate Area] (NC.ACG) || [BrainRegionNDM_NC_AL_VACG NDM.NC.AL.VACG] -> [BrainRegionNMA_NC_PMC_F2 NMA.NC.PMC.F2]||(unknown reference) || || [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex] (NC.AL.LPFC) || [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL] -> [BrainRegionNMA_NC_PMC_F5 NMA.NC.PMC.F5]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)] || || [BrainCenterNC_IPL Inferior Parietal Lobule] (NC.IPL) || [BrainRegionNPE_NC_IPL_SMW NPE.NC.IPL.SMW] -> [BrainRegionNMA_NC_PMC_F2 NMA.NC.PMC.F2]||[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846110/ Dual Auditory Processing (PPC -> DLPFC, abstract)] || || [BrainCenterNC_PG_APC Anterior Parietal Cortex] (NC.PG.APC) || [BrainRegionNCP_NC_PG_S1 NCP.NC.PG.S1] -> [BrainRegionNMA_NC_PMC_F2 NMA.NC.PMC.F2]||[http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (ParietalCortex -> FrontalCortex, abstract)] || || [BrainCenterNC_SPL Superior Parietal Lobule] (NC.SPL) || [BrainRegionNCP_NC_SPL_SA NCP.NC.SPL.SA] -> [BrainRegionNMA_NC_PMC_F2 NMA.NC.PMC.F2]||[http://ahuman.org/svn/ahengine/research/articles/Biological/2008-dorsal-stream.pdf 3 Visual Cortex Paths (SPL -> dPM, abstract)] || || [BrainCenterNC_STG Superior Temporal Gyrus] (NC.STG) || [BrainRegionNSA_NC_STG_A3 NSA.NC.STG.A3] -> [BrainRegionNMA_NC_PMC_F4 NMA.NC.PMC.F4]||[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846110/ Dual Auditory Processing (ST -> VLPFC, abstract)] || || [BrainCenterNMA_NC_SMC Supplementary Motor Cortex] (NMA.NC.SMC) || [BrainRegionNMA_NC_SMC_F3 NMA.NC.SMC.F3] -> [BrainRegionNMA_NC_PMC_F2 NMA.NC.PMC.F2]||[http://ahuman.org/svn/ahengine/research/articles/Biological/2008-dorsal-stream.pdf 3 Visual Cortex Paths (pre-SMA -> dPM, abstract)] || || [BrainCenterNSA_NC_IPS Intraparietal Sulcus] (NSA.NC.IPS) || [BrainRegionNSA_NC_IPS_AIP NSA.NC.IPS.AIP] -> [BrainRegionNMA_NC_PMC_F4 NMA.NC.PMC.F4]||[http://www.sciencedirect.com/science/article/pii/S0893608098000471 Primate Control of Grasping (AIP -> F4)] || || [BrainCenterNSA_NC_IT Inferotemporal Area] (NSA.NC.IT) || [BrainRegionNSA_NC_IT_TE NSA.NC.IT.TE] -> [BrainRegionNPE_NC_PMC_CFEF NPE.NC.PMC.CFEF]||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/saccades.jpg Saccades and smooth movements (TEF -> FEF, abstract)] || || [BrainCenterNSA_NC_TTG Transverse Temporal Gyrus] (NSA.NC.TTG) || [BrainRegionNSA_NC_TTG_A1 NSA.NC.TTG.A1] -> [BrainRegionNMA_NC_PMC_F7 NMA.NC.PMC.F7]||[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846110/ Dual Auditory Processing (A1 -> DLPFC, abstract)] || *External Outbound Center Connections:* || *Target Center* || *Sample Link* || *Reference* || || [BrainCenterFEC_FD_STA Subthalamus Area] (FEC.FD.STA) || [BrainRegionNPE_NC_PMC_AFEF NPE.NC.PMC.AFEF] -> [BrainRegionFEC_FD_STN_MED FEC.FD.STN.MED]||[http://www.neurology.org/content/70/21/1991/F2.expansion.html Functional subdivisions of the subthalamic nucleus (FEF -> STN, abstract)] || || [BrainCenterFEC_FT_BG Basal Ganglia] (FEC.FT.BG) || [BrainRegionNMA_NC_PMC_F2 NMA.NC.PMC.F2] -> [BrainRegionFEC_FT_PU_MED FEC.FT.PU.MED]||[http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)] || || [BrainCenterHL_RF Medullary Reticular Formation] (HL.RF) || [BrainRegionNPE_NC_PMC_AFEF NPE.NC.PMC.AFEF] -> [BrainRegionLRC_HL_PRF_GCR LRC.HL.PRF.GCR]||[http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> MRF, abstract)] || || [BrainCenterHT_RF Pontine Reticular Formation] (HT.RF) || [BrainRegionNPE_NC_PMC_AFEF NPE.NC.PMC.AFEF] -> [BrainRegionLRC_HT_PRF_RPO LRC.HT.PRF.RPO]||[http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] || || [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon] (MM.REF) || [BrainRegionNPE_NC_PMC_AFEF NPE.NC.PMC.AFEF] -> [BrainRegionLRC_MM_CJ LRC.MM.CJ]||[http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (FEF -> riMLF, abstract)] || || [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex] (NC.AL.LPFC) || [BrainRegionNMA_NC_PMC_F4 NMA.NC.PMC.F4] -> [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL]||[http://www.sciencedirect.com/science/article/pii/S1053810011000080 Cortico-Cortical Connectivity (MA -> PFC, abstract)] || || [BrainRegionNMA_NC_MC Motor Cortex] (NMA.NC.MC) || [BrainRegionNMA_NC_PMC_F2 NMA.NC.PMC.F2] -> [BrainRegionNMA_NC_MC NMA.NC.MC]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (PMC -> MC, abstract)] || || [BrainCenterNMA_NC_SMC Supplementary Motor Cortex] (NMA.NC.SMC) || [BrainRegionNMA_NC_PMC_F4 NMA.NC.PMC.F4] -> [BrainRegionNMA_NC_SMC_F3 NMA.NC.SMC.F3]||(unknown reference) ||