#summary Lateral Prefrontal Cortex @@[Home] -> [BiologicalLifeResearch] -> [BrainCenterNC_AL_LPFC] ---- This page covers biological details of component group Lateral Prefrontal Cortex. Component group is part of aHuman target integrated biological model. * *Top-down path to center*: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Lateral Prefrontal Cortex (NC.AL.LPFC) (see [OverallMindMaps Mind Maps]) * *Function*: High-level Rational Thinking Functions (generated) = Components = (generated) *Component items*: * *Mid-Dorsolateral Prefrontal Cortex* (NDM.NC.AL.DLPFC): Temporal Integration and working memory * [BrainRegionNDM_NC_AL_DLPFCR Rostral Mid-Dorsolateral Prefrontal Cortex] (NDM.NC.AL.DLPFCR): Cognitive control and monitoring to resolve conflict in information processing and competing response plans * [BrainRegionNDM_NC_AL_DLPFCL Lateral Mid-Dorsolateral Prefrontal Cortex] (NDM.NC.AL.DLPFCL): Cognitive control related to stimulus processing and selection of relevant information for behavior * *Ventrolateral Prefrontal Cortex* (NC.AL.VLPFC) * [BrainRegionNDM_NC_AL_IPG Inferior Prefrontal Gyrus] (NDM.NC.AL.IPG): Processing of syntax in oral and sign languages * *Broca's Area* (NPE.NC.PFC.BRA): Speech Engine * [BrainRegionNPE_NC_BRA_PO Broca's Area Pars Opercularis] (NPE.NC.BRA.PO): Speech Engine * [BrainRegionNPE_NC_BRA_PT Broca's Area Pars Triangularis] (NPE.NC.BRA.PT): Language production and prefrontal associational integration, propositional language comprehension = Connectivity = (generated) *Internal Regions Connections:* unavailable || *Source Region* || *Target Region* || *Reference* || || [BrainRegionNDM_NC_AL_IPG Inferior Prefrontal Gyrus] (NDM.NC.AL.IPG) || [BrainRegionNDM_NC_AL_DLPFCL Lateral Mid-Dorsolateral Prefrontal Cortex] (NDM.NC.AL.DLPFCL) || [http://www.frontiersin.org/Human_Neuroscience/10.3389/fnhum.2012.00184/full Directed Effort Network (fPole -> DLPFC, abstract)] || *External Connections:* unavailable *External Inbound Center Connections:* || *Source Center* || *Sample Link* || *Reference* || || [BrainCenterFD_TH_CR Cognitive Thalamus] (FD.TH.CR) || [BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM] -> [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)] || || [BrainCenterFD_TH_SR Sensory Thalamus] (FD.TH.SR) || [BrainRegionNPE_FD_TH_MPV NPE.FD.TH.MPV] -> [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL]||[http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Saccadic Vision (Thalamus -> FrontalCortex, abstract)] || || [BrainCenterLLC_HT_CRC Cerebellar Complex] (LLC.HT.CRC) || [BrainRegionLLC_HT_CR_DN LLC.HT.CR.DN] -> [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL]||(unknown reference) || || [BrainCenterNC_ACG Anterior Cingulate Area] (NC.ACG) || [BrainRegionNDM_NC_AL_VACG NDM.NC.AL.VACG] -> [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR]||[http://www.pnas.org/content/107/40/17071/F1.expansion.html Role for serotonin in moral behavior (ACG -> LPFC, abstract)] || || [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex] (NC.AL.OMPFC) || [BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC] -> [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)] || || [BrainCenterNC_INS Insular Cortex] (NC.INS) || [BrainRegionNCP_NC_INS_AIC NCP.NC.INS.AIC] -> [BrainRegionNDM_NC_AL_IPG NDM.NC.AL.IPG]||[http://www.frontiersin.org/Human_Neuroscience/10.3389/fnhum.2012.00184/full Directed Effort Network (Insula -> fPole, abstract)] || || [BrainCenterNC_IPL Inferior Parietal Lobule] (NC.IPL) || [BrainRegionNPE_NC_IPL_MST NPE.NC.IPL.MST] -> [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR]||[http://www.sciencedirect.com/science/article/pii/S1053810011000080 Cortico-Cortical Connectivity (PTHA -> PFC, abstract)] || || [BrainCenterNC_LOBE_OCC Occipital Lobe] (NC.LOBE.OCC) || [BrainRegionNSA_NC_OCC_V2TN NSA.NC.OCC.V2TN] -> [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL]||[http://www.sciencedirect.com/science/article/pii/S1053810011000080 Cortico-Cortical Connectivity (VA -> PFC, abstract)] || || [BrainCenterNC_MPL Medial Parietal Lobule] (NC.MPL) || [BrainRegionNCP_NC_MPL_RSC NCP.NC.MPL.RSC] -> [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract)] || || [BrainCenterNC_PMC Premotor Cortex] (NC.PMC) || [BrainRegionNMA_NC_PMC_F4 NMA.NC.PMC.F4] -> [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL]||[http://www.sciencedirect.com/science/article/pii/S1053810011000080 Cortico-Cortical Connectivity (MA -> PFC, abstract)] || || [BrainCenterNC_STG Superior Temporal Gyrus] (NC.STG) || [BrainRegionNCP_NC_TPC NCP.NC.TPC] -> [BrainRegionNDM_NC_AL_IPG NDM.NC.AL.IPG]||[http://www.sciencedirect.com/science/article/pii/S1364661312002823 Language-Related Regions (TC -> vIFC)] || || [BrainCenterNSA_NC_IPS Intraparietal Sulcus] (NSA.NC.IPS) || [BrainRegionNPE_NC_IPS_LIP NPE.NC.IPS.LIP] -> [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR]||[http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (PEF -> DLPFC, abstract)] || || [BrainCenterNSA_NC_IT Inferotemporal Area] (NSA.NC.IT) || [BrainRegionNSA_NC_IT_TE NSA.NC.IT.TE] -> [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL]||[http://ahuman.org/svn/ahengine/research/articles/Biological/2008-dorsal-stream.pdf 3 Visual Cortex Paths (IT -> LPC, abstract)] || *External Outbound Center Connections:* || *Target Center* || *Sample Link* || *Reference* || || [BrainCenterFD_TH_MR Motor Thalamus] (FD.TH.MR) || [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL] -> [BrainRegionNMA_FD_TH_VA NMA.FD.TH.VA]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (LPFC -> TH, abstract)] || || [BrainCenterFEC_FT_BG Basal Ganglia] (FEC.FT.BG) || [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL] -> [BrainRegionFEC_FT_CN_HD FEC.FT.CN.HD]||[http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)] || || [BrainCenterHT_RF Pontine Reticular Formation] (HT.RF) || [BrainRegionNPE_NC_BRA_PO NPE.NC.BRA.PO] -> [BrainRegionLLC_HT_PRF_RTMG LLC.HT.PRF.RTMG]||[http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] || || [BrainCenterNC_ACG Anterior Cingulate Area] (NC.ACG) || [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR] -> [BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (LPFC -> ACG, abstract)] || || [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex] (NC.AL.OMPFC) || [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR] -> [BrainRegionNDM_NC_AL_VMPFC NDM.NC.AL.VMPFC]||[https://brmlab.cz/project/brain_hacking/tdcs/pfc Fear regulation (dlPFC -> vmPFC, abstract)] || || [BrainCenterNC_IPL Inferior Parietal Lobule] (NC.IPL) || [BrainRegionNPE_NC_BRA_PT NPE.NC.BRA.PT] -> [BrainRegionNPE_NC_IPL_SMW NPE.NC.IPL.SMW]||[http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html Cortical Auditory System (IFC44 -> IPL40, abstract)] || || [BrainCenterNC_PMC Premotor Cortex] (NC.PMC) || [BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL] -> [BrainRegionNMA_NC_PMC_F5 NMA.NC.PMC.F5]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)] || || [BrainCenterNMA_NC_SMC Supplementary Motor Cortex] (NMA.NC.SMC) || [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR] -> [BrainRegionNMA_NC_SMC_F6 NMA.NC.SMC.F6]||[http://www.sciencedirect.com/science/article/pii/S0893608098000471 Primate Control of Grasping (46 -> F6, abstract)] ||