#summary Mesencephalic Reticular Formation
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This page covers biological details of component group Mesencephalic Reticular Formation.
Component group is part of aHuman target integrated biological model.
* *Top-down path to center*: Midbrain Mesencephalon -> Mesencephalic Reticular Formation (MM.RF) (see [OverallMindMaps Mind Maps])
* *Function*:
* *Notes to function*: Saccades, fixation, gaze holding and vergence. Space-time coordinated rapid eye movements
(generated)
= Components =
(generated)
*Component items*:
* *Mesencephalic Reticular Formation, Medial Column* (MM.RF.MED)
* [BrainRegionLRC_MM_CNF Cuneiform Nucleus] (LRC.MM.CNF): Passive coping strategy to novel, painful or threatening stimuli
* [BrainRegionLRC_MM_SCNF Subcuneiform Nucleus] (LRC.MM.SCNF): Initiation of gait, feedback control of saccade accuracy
* *Mesencephalic Reticular Formation, Midline Column* (MM.RF.MID)
* [BrainRegionLMC_MM_RP_SUC Superior Central Raphe Nucleus] (LMC.MM.RP.SUC): Block or temporarily suspend mnemonic processes in the hippocampus; Hallucinations
* [BrainRegionLMC_MM_RP_DRN Dorsal Raphe Nucleus] (LMC.MM.RP.DRN): Regulation of sleep and mood
* [BrainRegionLRC_MM_RP_RIP Raphe Interpositus Nucleus] (LRC.MM.RP.RIP): Premotor network for saccades
* [BrainRegionLMC_HP_RP_LI Raphe Nucleus Linearis] (LMC.HP.RP.LI): Release of 5-HT was only obtained on stimulation of this nucleus
= Connectivity =
(generated)
*Internal Regions Connections:*
|| *Source Region* || *Target Region* || *Reference* ||
|| [BrainRegionLMC_HP_RP_LI Raphe Nucleus Linearis] (LMC.HP.RP.LI) || [BrainRegionLMC_MM_RP_DRN Dorsal Raphe Nucleus] (LMC.MM.RP.DRN) || (unknown reference) ||
|| [BrainRegionLRC_MM_RP_RIP Raphe Interpositus Nucleus] (LRC.MM.RP.RIP) || [BrainRegionLRC_MM_SCNF Subcuneiform Nucleus] (LRC.MM.SCNF) || (unknown reference) ||
*External Connections:*
*External Inbound Center Connections:*
|| *Source Center* || *Sample Link* || *Reference* ||
|| [BrainCenterBMA_SC_PH Posterior/Dorsal Horn] (BMA.SC.PH) || [BrainRegionLPC_SC_PH_CL LPC.SC.PH.CL] -> [BrainRegionLRC_MM_CNF LRC.MM.CNF]||(unknown reference) ||
|| [BrainCenterFAM_FD_HB Habenula] (FAM.FD.HB) || [BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED] -> [BrainRegionLMC_MM_RP_DRN LMC.MM.RP.DRN]||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN)] ||
|| [BrainCenterFD_TH_CR Cognitive Thalamus] (FD.TH.CR) || [BrainRegionLLC_FD_TH_SF LLC.FD.TH.SF] -> [BrainRegionLMC_MM_RP_DRN LMC.MM.RP.DRN]||(unknown reference) ||
|| [BrainCenterHL_MN Myelencephalic Motor Nuclei] (HL.MN) || [BrainRegionLRC_HL_NPH LRC.HL.NPH] -> [BrainRegionLRC_MM_SCNF LRC.MM.SCNF]||(unknown reference) ||
|| [BrainCenterHL_RF Medullary Reticular Formation] (HL.RF) || [BrainRegionLRC_HL_PRF_GCR LRC.HL.PRF.GCR] -> [BrainRegionLRC_MM_SCNF LRC.MM.SCNF]||(unknown reference) ||
|| [BrainCenterHT_TG Pontine Tegmental Nuclei] (HT.TG) || [BrainRegionFEC_HT_TG_IPD FEC.HT.TG.IPD] -> [BrainRegionLMC_MM_RP_DRN LMC.MM.RP.DRN]||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> DRN)] ||
|| [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon] (MM.REF) || [BrainRegionLRC_MM_SC_SUP LRC.MM.SC.SUP] -> [BrainRegionLRC_MM_RP_RIP LRC.MM.RP.RIP]||[http://www.sciencedirect.com/science/article/pii/S0006899301025987 Horizontal saccades and smooth pursuit movements (SC -> RIP, abstract)] ||
|| [BrainCenterNMA_NC_SMC Supplementary Motor Cortex] (NMA.NC.SMC) || [BrainRegionNPE_NC_SMC_SEF NPE.NC.SMC.SEF] -> [BrainRegionLRC_MM_RP_RIP LRC.MM.RP.RIP]||[http://www.sciencedirect.com/science/article/pii/S0006899301025987 Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract)] ||
*External Outbound Center Connections:*
|| *Target Center* || *Sample Link* || *Reference* ||
|| [BrainCenterFAM_FT_SEP Septal Nuclei] (FAM.FT.SEP) || [BrainRegionLMC_MM_RP_SUC LMC.MM.RP.SUC] -> [BrainRegionFAM_FT_SEP_LT FAM.FT.SEP.LT]||(unknown reference) ||
|| [BrainCenterFD_HT Hypothalamus] (FD.HT) || [BrainRegionLMC_MM_RP_SUC LMC.MM.RP.SUC] -> [BrainRegionFMM_FD_MB_MMB FMM.FD.MB.MMB]||(unknown reference) ||
|| [BrainCenterFD_TH_CR Cognitive Thalamus] (FD.TH.CR) || [BrainRegionLMC_MM_RP_DRN LMC.MM.RP.DRN] -> [BrainRegionNDM_FD_TH_PV NDM.FD.TH.PV]||(unknown reference) ||
|| [BrainCenterFEC_FD_STA Subthalamus Area] (FEC.FD.STA) || [BrainRegionLMC_MM_RP_SUC LMC.MM.RP.SUC] -> [BrainRegionFEC_FD_STN_ICD FEC.FD.STN.ICD]||(unknown reference) ||
|| [BrainCenterHL_PSN Myelencephalic Parasympathetic Nuclei] (HL.PSN) || [BrainRegionLRC_MM_CNF LRC.MM.CNF] -> [BrainRegionLAC_HL_VGN LAC.HL.VGN]||(unknown reference) ||
|| [BrainCenterHL_RF Medullary Reticular Formation] (HL.RF) || [BrainRegionLRC_MM_CNF LRC.MM.CNF] -> [BrainRegionLRC_HL_PRF_GCR LRC.HL.PRF.GCR]||(unknown reference) ||
|| [BrainCenterHT_MN Metencephalic Motor Nuclei] (HT.MN) || [BrainRegionLRC_MM_CNF LRC.MM.CNF] -> [BrainRegionLRC_HT_KFN LRC.HT.KFN]||(unknown reference) ||
|| [BrainCenterHT_RF Pontine Reticular Formation] (HT.RF) || [BrainRegionLRC_MM_RP_RIP LRC.MM.RP.RIP] -> [BrainRegionLRC_HT_PRF_RPO LRC.HT.PRF.RPO]||[http://www.sciencedirect.com/science/article/pii/S0006899301025987 Horizontal saccades and smooth pursuit movements (RIP -> PPRF, abstract)] ||