#summary Hippocampal Formation
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This page covers biological details of component group Hippocampal Formation.
Component group is part of aHuman target integrated biological model.
* *Top-down path to center*: Forebrain Telencephalon -> Hippocampal Formation (FMM.FT.HF) (see [OverallMindMaps Mind Maps])
* *Function*: Attention and short-term to long-term memory conversion
* *Notes to function*: allocortex
(generated)
= Components =
(generated)
*Component items*:
* *Hippocampus* (FMM.FT.HC)
* [BrainRegionFMM_FT_HC_DG Dentate Gyrus] (FMM.FT.HC.DG): Distinguishing multiple instances of similar events
* *Ventrolateral Cornu Ammonis of Hippocampus* (FMM.FT.HC.CA1): Representing sequences of episodic memory - long-term
* [BrainRegionFMM_FT_HC_CA1P Proximal CA1 of Hippocampus] (FMM.FT.HC.CA1P): Long-term memory, spatial
* [BrainRegionFMM_FT_HC_CA1M Middle CA1 of Hippocampus] (FMM.FT.HC.CA1M): Long-term memory, synchronize
* [BrainRegionFMM_FT_HC_CA1D Distal CA1 of Hippocampus] (FMM.FT.HC.CA1D): Long-term memory, motivational
* [BrainRegionFMM_FT_HC_CA2 Dorsolateral Cornu Ammonis of Hippocampus] (FMM.FT.HC.CA2): Gate controlled by the activity of the supramammillary nucleus to control signal propagation between HC lamines
* *Dorsomedial Cornu Ammonis of Hippocampus* (FMM.FT.HC.CA3): Representing sequences of episodic memory - short-term
* [BrainRegionFMM_FT_HC_CA3P Proximal CA3 of Hippocampus] (FMM.FT.HC.CA3P): Representing sequences of episodic memory, spatial
* [BrainRegionFMM_FT_HC_CA3M Middle CA3 of Hippocampus] (FMM.FT.HC.CA3M): Representing sequences of episodic memory, synchronize
* [BrainRegionFMM_FT_HC_CA3D Distal CA3 of Hippocampus] (FMM.FT.HC.CA3D): Representing sequences of episodic memory, motivational
* *Subiculum* (FMM.FT.HF.SUB): Spatial navigation and mnemonic processing
* [BrainRegionFMM_FT_HF_SUBP Proximal Subiculum] (FMM.FT.HF.SUBP): Controlling hypothalamic-pituitary-adrenal (HPA) axis
* [BrainRegionFMM_FT_HF_SUBM Middle Subiculum] (FMM.FT.HF.SUBM): Dynamic bridging of temporal intervals
* [BrainRegionFMM_FT_HF_SUBD Distal Subiculum] (FMM.FT.HF.SUBD): Providing coarse representation of space
= Connectivity =
(generated)
*Internal Regions Connections:*
|| *Source Region* || *Target Region* || *Reference* ||
|| [BrainRegionFMM_FT_HC_CA1D Distal CA1 of Hippocampus] (FMM.FT.HC.CA1D) || [BrainRegionFMM_FT_HF_SUBP Proximal Subiculum] (FMM.FT.HF.SUBP) || [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (CA1 -> SUB, abstract)] ||
|| [BrainRegionFMM_FT_HC_CA1M Middle CA1 of Hippocampus] (FMM.FT.HC.CA1M) || [BrainRegionFMM_FT_HF_SUBM Middle Subiculum] (FMM.FT.HF.SUBM) || [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (CA1 -> SUB, abstract)] ||
|| [BrainRegionFMM_FT_HC_CA1P Proximal CA1 of Hippocampus] (FMM.FT.HC.CA1P) || [BrainRegionFMM_FT_HF_SUBD Distal Subiculum] (FMM.FT.HF.SUBD) || [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (CA1 -> SUB, abstract)] ||
|| [BrainRegionFMM_FT_HC_CA2 Dorsolateral Cornu Ammonis of Hippocampus] (FMM.FT.HC.CA2) || [BrainRegionFMM_FT_HC_CA1D Distal CA1 of Hippocampus] (FMM.FT.HC.CA1D) || [http://www.sciencedirect.com/science/article/pii/S030645220600755X Flow of impulses in hippocampal region (CA2 -> CA1, abstract)] ||
|| || [BrainRegionFMM_FT_HC_CA1M Middle CA1 of Hippocampus] (FMM.FT.HC.CA1M) || [http://www.sciencedirect.com/science/article/pii/S030645220600755X Flow of impulses in hippocampal region (CA2 -> CA1, abstract)] ||
|| || [BrainRegionFMM_FT_HC_CA1P Proximal CA1 of Hippocampus] (FMM.FT.HC.CA1P) || [http://www.sciencedirect.com/science/article/pii/S030645220600755X Flow of impulses in hippocampal region (CA2 -> CA1, abstract)] ||
|| [BrainRegionFMM_FT_HC_CA3D Distal CA3 of Hippocampus] (FMM.FT.HC.CA3D) || [BrainRegionFMM_FT_HC_CA1P Proximal CA1 of Hippocampus] (FMM.FT.HC.CA1P) || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (CA3 -> CA1, abstract)] ||
|| || [BrainRegionFMM_FT_HC_CA2 Dorsolateral Cornu Ammonis of Hippocampus] (FMM.FT.HC.CA2) || [http://www.sciencedirect.com/science/article/pii/S1571064507000243 KIV model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)] ||
|| [BrainRegionFMM_FT_HC_CA3M Middle CA3 of Hippocampus] (FMM.FT.HC.CA3M) || [BrainRegionFMM_FT_HC_CA1M Middle CA1 of Hippocampus] (FMM.FT.HC.CA1M) || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (CA3 -> CA1, abstract)] ||
|| || [BrainRegionFMM_FT_HC_CA2 Dorsolateral Cornu Ammonis of Hippocampus] (FMM.FT.HC.CA2) || [http://www.sciencedirect.com/science/article/pii/S1571064507000243 KIV model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)] ||
|| [BrainRegionFMM_FT_HC_CA3P Proximal CA3 of Hippocampus] (FMM.FT.HC.CA3P) || [BrainRegionFMM_FT_HC_CA1D Distal CA1 of Hippocampus] (FMM.FT.HC.CA1D) || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (CA3 -> CA1, abstract)] ||
|| || [BrainRegionFMM_FT_HC_CA2 Dorsolateral Cornu Ammonis of Hippocampus] (FMM.FT.HC.CA2) || [http://www.sciencedirect.com/science/article/pii/S1571064507000243 KIV model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)] ||
|| [BrainRegionFMM_FT_HC_DG Dentate Gyrus] (FMM.FT.HC.DG) || [BrainRegionFMM_FT_HC_CA3D Distal CA3 of Hippocampus] (FMM.FT.HC.CA3D) || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (DG -> CA3, abstract)] ||
|| || [BrainRegionFMM_FT_HC_CA3M Middle CA3 of Hippocampus] (FMM.FT.HC.CA3M) || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (DG -> CA3, abstract)] ||
|| || [BrainRegionFMM_FT_HC_CA3P Proximal CA3 of Hippocampus] (FMM.FT.HC.CA3P) || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (DG -> CA3, abstract)] ||
*External Connections:*
*External Inbound Center Connections:*
|| *Source Center* || *Sample Link* || *Reference* ||
|| [BrainCenterFAM_FT_AM Amygdala] (FAM.FT.AM) || [BrainRegionFAM_FT_AM_BP FAM.FT.AM.BP] -> [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D]||[https://books.google.ru/books?id=P3fSBwAAQBAJ Detailed amygdalohippocampal projections (Bpc -> CA1D)] ||
|| [BrainCenterFAM_FT_SEP Septal Nuclei] (FAM.FT.SEP) || [BrainRegionFAM_FT_SEP_DBB FAM.FT.SEP.DBB] -> [BrainRegionFMM_FT_HC_CA2 FMM.FT.HC.CA2]||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)] ||
|| [BrainCenterFD_HT Hypothalamus] (FD.HT) || [BrainRegionLAC_FD_HT_SUM LAC.FD.HT.SUM] -> [BrainRegionFMM_FT_HC_CA2 FMM.FT.HC.CA2]||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)] ||
|| [BrainCenterFD_TH_CR Cognitive Thalamus] (FD.TH.CR) || [BrainRegionFMM_FD_TH_RE FMM.FD.TH.RE] -> [BrainRegionFMM_FT_HC_CA1M FMM.FT.HC.CA1M]||[http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (MID -> HC, abstract)] ||
|| [BrainCenterFD_TH_MR Motor Thalamus] (FD.TH.MR) || [BrainRegionFMM_FD_TH_LD FMM.FD.TH.LD] -> [BrainRegionFMM_FT_HC_CA1P FMM.FT.HC.CA1P]||[http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (LD -> HC, abstract)] ||
|| [BrainCenterFMM_NC_PHP Posterior Parahippocampal Gyrus] (FMM.NC.PHP) || [BrainRegionFMM_NC_PH_POR FMM.NC.PH.POR] -> [BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD]||(unknown reference) ||
|| [BrainCenterHT_MN Metencephalic Motor Nuclei] (HT.MN) || [BrainRegionLRC_HT_NSC LRC.HT.NSC] -> [BrainRegionFMM_FT_HC_DG FMM.FT.HC.DG]||(unknown reference) ||
|| [BrainCenterHT_TG Pontine Tegmental Nuclei] (HT.TG) || [BrainRegionFEC_HT_TG_IPD FEC.HT.TG.IPD] -> [BrainRegionFMM_FT_HC_CA3P FMM.FT.HC.CA3P]||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (IPN -> Hippo, abstract)] ||
|| [BrainRegionLMC_MM_VTA Ventral Tegmental Area] (LMC.MM.VTA) || [BrainRegionLMC_MM_VTA LMC.MM.VTA] -> [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D]||[http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (VTA -> HC, abstract)] ||
|| [BrainCenterNC_IPL Inferior Parietal Lobule] (NC.IPL) || [BrainRegionNPE_NC_IPL_MST NPE.NC.IPL.MST] -> [BrainRegionFMM_FT_HC_CA1P FMM.FT.HC.CA1P]||[http://www.sciencedirect.com/science/article/pii/S0149763409002061 Contribution of hippocampal region CA3 to consciousness (IPL -> CA1, abstract)] ||
|| [BrainCenterNC_MPL Medial Parietal Lobule] (NC.MPL) || [BrainRegionNCP_NC_MPL_PSCG NCP.NC.MPL.PSCG] -> [BrainRegionFMM_FT_HC_CA1P FMM.FT.HC.CA1P]||[http://www.nature.com/nrn/journal/v5/n7 Feeling (CG -> HC, abstract)] ||
|| [BrainCenterNC_PHA_RH Rhinal Cortex] (NC.PHA.RH) || [BrainRegionFMM_NC_PH_LEC FMM.NC.PH.LEC] -> [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D]||[http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (ET -> CA1, abstract)] ||
*External Outbound Center Connections:*
|| *Target Center* || *Sample Link* || *Reference* ||
|| [BrainCenterFAM_FT_AM Amygdala] (FAM.FT.AM) || [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D] -> [BrainRegionFAM_FT_AM_LAVM FAM.FT.AM.LAVM]||[https://brmlab.cz/project/brain_hacking/tdcs/pfc Fear regulation (Hippocampus -> LA, abstract)] ||
|| [BrainCenterFAM_FT_SEP Septal Nuclei] (FAM.FT.SEP) || [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D] -> [BrainRegionFAM_FT_SEP_LT FAM.FT.SEP.LT]||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Hippo -> Septum, abstract)] ||
|| [BrainCenterFD_HT Hypothalamus] (FD.HT) || [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D] -> [BrainRegionLAC_FD_HT_MPO LAC.FD.HT.MPO]||[http://www.nature.com/nrn/journal/v5/n7 Feeling (HC -> HT, abstract)] ||
|| [BrainCenterFD_TH_CR Cognitive Thalamus] (FD.TH.CR) || [BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD] -> [BrainRegionFMM_FD_TH_AV FMM.FD.TH.AV]||[http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/ Thalamocortical relationships (s1A -> A, abstract)] ||
|| [BrainCenterFD_TH_MR Motor Thalamus] (FD.TH.MR) || [BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD] -> [BrainRegionFMM_FD_TH_LD FMM.FD.TH.LD]||[http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (Sub -> LD, abstract)] ||
|| [BrainCenterFEC_FT_BG Basal Ganglia] (FEC.FT.BG) || [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D] -> [BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE]||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (CA1 -> NACC, abstract)] ||
|| [BrainCenterFMM_NC_PHA_RS Retrosubicular Area] (FMM.NC.PHA.RS) || [BrainRegionFMM_FT_HC_CA1P FMM.FT.HC.CA1P] -> [BrainRegionFMM_NC_PH_PAS FMM.NC.PH.PAS]||(unknown reference) ||
|| [BrainCenterFMM_NC_PHP Posterior Parahippocampal Gyrus] (FMM.NC.PHP) || [BrainRegionFMM_FT_HC_CA1P FMM.FT.HC.CA1P] -> [BrainRegionFMM_NC_PH_POR FMM.NC.PH.POR]||[http://www.sciencedirect.com/science/article/pii/S0149763411001722 Entorhinal Cortex Inputs and Outputs (CA1 -> TFTH, abstract)] ||
|| [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex] (NC.AL.OMPFC) || [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D] -> [BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR]||[http://www.sciencedirect.com/science/article/pii/S030100820900183X Simplified model of hippocampal formation anatomy (CA1 -> mPFC, abstract)] ||
|| [BrainCenterNC_MPL Medial Parietal Lobule] (NC.MPL) || [BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD] -> [BrainRegionNCP_NC_MPL_RSC NCP.NC.MPL.RSC]||[http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html McNaughton Spatial Processing Network (SUB -> PCGRSP, abstract)] ||
|| [BrainCenterNC_PHA_RH Rhinal Cortex] (NC.PHA.RH) || [BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD] -> [BrainRegionFMM_NC_PH_LEC FMM.NC.PH.LEC]||[http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (SUB -> EC, abstract)] ||