<pre style="color: green">Biological Life Research</pre>
[[Home]] -> [[BiologicalLifeResearch]] -> [[BiologicalArchitecture]] -> [[BiologicalArchitectureModulation]]

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This page covers biological principles of non-specific modulation.

== Overview ==

* mind contains components which affect large mind areas at once
** these components are affected by quite specific circuits and change the mode in which brain is operating
** components are utilizing specific neurotransmitters - DA, 5HT, ACh, NE for its efferent connections
** non-specific modulators allow the mind to work as a single unit, by means of coordinating internal parts
* sample behavior of modulators:
** DA circuit to speed up execution: habenula -> SNc -> striatum (D1+,D2-) -> ventroanterior thalamus (reduce inhibition) -> M1 (increased activity) -> motoneuron
** 5HT circuit to go asleep: habenula -> dorsal raphe nucleus -> paraventricular thalamus -> hypothalamus -> body
** ACh circuit to control perception vs imaginaton: amygdala -> basal nucleus of Meynert -> prefrontal cortex (-feedforward,+feedback)
** NE circuit to adopt to pain: spinal cord substantia gelatinosa -> lateral spinal nucleus -> hypothalamus -> locus coeruleus -> spinal cord substantia gelatinosa (inhibit)